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Shire Announces European Filings of SPD476 (Mesalazine) for ...... "Currently there is no once-daily oral treatment for Shire also
recently filed a New Drug Submission for SPD476 with Health Canada.SPD476 is the only the exclusive rights to develop and commercialize SPD476 in
the US, Canada, Europe (excluding Italy) and the Pacific Rim. Giuliani S.p.A. retains the development and commercialization rights to SPD476 in Italy. MMX
was developed by Cosmo S.p.A.Notes to editorsSPD476SPD476 is a novel, high-dose 5-aminosalicylic acid (5-ASA; mesalazine) in
a delayed and extended release formulation (MMX) being studied for the
induction and maintenance of remission of active, mild-to-moderate ulcerative
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