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Drugs formerly contraindicated for inflammatory bowel disease ...

...Study findings show that NSAIDs were well-tolerated, with COX-2 inhibitors offering the most effective pain relief in this group.

"In the past, physicians have considered These studies represent an important advance for patients with inflammatory bowel disease and their gastroenterologists searching for safe medications to help with pain relief," said Joshua R.

Korzenik, MD, author of an accompanying editorial from Massachusetts General Hospital in Boston.

"Patients with However, some researchers have argued that these painkillers have negative effects on IBD patients in remission.

According to a study in this month's issue of Clinical Gastroenterology and Hepatology, patients with IBD who use NSAIDs tolerate the drugs well and less than one in three patients experiences a flare-up in symptoms.

Furthermore, the study shows COX-2 inhibitors, previously thought to cause symptom recurrence in IBD patients, significantly reduce the likelihood of disease relapse.

To date, this is the most comprehensive study to address the effects of NSAID...

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