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Short spell of Celebrex may be safe for IBD

...However, another study showed that use of older, nonselective anti-inflammatory agents can quickly induce relapse in patients with Crohn's disease and However, this study also found that short-term treatment with a Celebrex-like drug or with low-dose aspirin is well tolerated.The results of the two studies may set the stage for larger, prospective trials of COX-2 inhibitors in patients with inflammatory bowel disease (IBD), researchers say.

However, such trials will most likely have to wait until the cardiovascular disease risk from COX-2 inhibitors has been clarified."In general," Dr.

William J.

Sandborn told Reuters Health, "gastroenterologists have counseled patients with IBD to not take anti-inflammatory drugs.

But when the COX-2 inhibitors came out, we wondered if the risk would be different."To investigate, Sandborn, from Mayo Clinic in Rochester, Minnesota, and colleagues randomly assigned 222 patients with Read more...

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