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Novartis provides update on regulatory status of Zelnorm? in ...

...Gastroenterology 2004; 126:1657-1664.

[10] Grider JR, Foxx-Orenstein AE, Jin J-G.

5-Hydroxytryptamine4 receptor agonists initiate the peristaltic reflex in human, rat and guinea-pig intestine.

Gastroenterology 1998; 115:370-380.

[11] M�ller-Lissner SA, Fumagalli I, Bardhan KD, Pace F, Pecher E, Nault B, et al.

Tegaserod, a 5-HT4 receptor partial agonist, relieves symptoms of irritable bowel syndrome in patients with abdominal pain, bloating and constipation.

Aliment Pharacol Ther 2001;15:1655-1666 [12] Prather CM, Camilleri M, Zinsmeister AR, McKinzie S, Thomforde G.

Tegaserod accelerates orocecal transit in patients with constipation-predominant irritable bowel syndrome.

Gastroenterology 2000; 118:463-468.

[13] Coffin B, Farmachidi JP, Rueegg P, Bastie A, Bouhassira D.

Tegaserod, a 5-HT4 receptor partial agonist, decreases sensitivity to rectal distension in healthy subjects.

Aliment Pharmacol Ther 2003; 17:577-585.

[14] Lefkowitz M, Shi Y, Schmitt C, Krumholz S, Tanghe J.

The 5-HT4 partial agonist, tegaserod, improves abdominal discomfort/pain and normalizes altered bowel function in irritable bowel syndrome (IBS).

Am J Gastroenterol 1999; 94:266.

[15] Novick J, Miner P, Krause R, Glebas K, Bliesath H, Ligozio G et al.

A randomized, double-blind, placebo-controlled trial of tegaserod in female patients suffering from irritable bowel syndrome with constipation.

Aliment Pharmacol Ther 2002; 16:1877-1888.

[16] Kellow J, ...

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