Ulcerative Colitis

An effective drug would greatly improve the quality of life for those receiving cancer treatment.

Also, by reducing the incidence and/or severity of mucositis, this would allow higher therapeutic doses to be administered and lead to more effective treatment.

Over one million of the cancer patients treated each year suffer from mucositis and the potential market for drugs to prevent/treat mucositis effectively is estimated to be in excess of $500 million per annum.

WHO (World Health Organisation) Oral Mucositis Grades The WHO is a 5 point scale ranging from 0 (no mucositis) to Grade 4 (unable to take fluids or solids by mouth).

Intermediate points on the scale include other components, such as: ulceration, pain and bleeding.

Western Consortium for Cancer Nursing Research (WCCNR) Grades The WCCNR is a 4 point scale, ranging from 0 (no mucositis), to Grade 3 (includes: ulceration, bleeding, infection, inability to take fluids and solids by mouth, and pain).

Intermediate points include all these symptoms, but with lower degrees of severity.

Autologous Peripheral Blood Stem Cell Transplantation (PBSCT) Autologous PBSCT involves removal of some stem cells from the blood of a c...

The cause of these diseases is poorly understood and no current management strategy is effective.

Current treatments do not provide a cure, and all produce significant unwanted side effects.

The disease usually recurs, with relapse rates of up to 80 per cent within the first year post-remission.

On this basis, the most effective management strategy is to devise improved maintenance therapy and treatment regimens which prolong the periods of remission without unwanted side effects.

Previous animal studies indicated NV-52 appears to be suited as a maintenance therapy to prevent relapse of disease.

Novogen is an Australian biopharmaceutical company specialising in the development of therapeutics based on the isoflavonoid chemical structure.

The Company is developing a range of therapeutics across the fields of oncology, cardiovascular disease and inflammatory diseases and phenoxodiol, its lead anti-cancer agent is currently in advanced Phase II clinical trialing with its US listed subsidiary Marshall Edwards Inc.

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More information on the Novogen Group can be found at http://www.novogen.com and http://www.marshalledwardsinc.com .

Under U.S.

law, an investigational drug cannot be marketed until it has be...

Her daughter was diagnosed with Crohn's disease at age 5.Rhonda Miller, now 20 and a sophomore at Miami University, said she will go along as part of the supporting crew to help the riders."I will probably be handing out water and stuff,'' Rhonda said.

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We are supposed to ride 70 miles a day in the bike ride.''She has to get sponsors to help raise a minimu...